Abatacept

1. Product Name: Abatacept 2. Protein content: 30mg/ml up 3. Quality: Medicine Grade

4. Specification of Abatacept

Items	Specifications	Results
Protein content	≥30mg/ml	37.01 mg/ml
Biological activity	≥400AU/mg	484AU/mg
Purity by Electrophoresis	Purity of monomer ≥95%	99.8%
Purity by SEC-HPLC	≥95%	99.6%
Molecular weight	42~52kDa	50.0kDa
UV absorption	Max.at 280nm ±3nm	277.3nm
Isoelectric Point	4.8±0.5, identical to that of reference standard	complies
Content of Sialic acid	100%±30% of that of the reference standard	112%
Residue of exogenous DNA	≤10pg/mg protein	Complies
Residue of CHO host cell protein	No more than 0.03% of total protein	0.00002%
Baxterial endotoxin	<0.1 EU/mg protein	< 0.05EU/mg
Peptide map	Identical to that of reference standard	Complies
Resideue of rProteinA	Not more than 0.01% of total protein	Complies
Sequence of 15 Amino Acid at N-terminal	Met-His-Val-Ala-Gln-Pro=Ala-Val-Val-Leu-Ala-Ser-Ser-Arg-Gly

Conclusion: The quality of this batch bulk product complies with Specification

5. Function:

Abatacept is a synthesized proteins by technology of recombinant DNA. it is a kind of biological agents.

Abatacept is mainly to apply to the treatment of rheumatoid arthritis (RA)

6. About cooperation

As a high-tech content biological agents, sincerely we can delevop successful long-term cooperation for Abatacept  preparation. we can support each other

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Sinoway's Advantages:

(1) ISO 9001:2008 certificated company

(2) 26 years in pharmaceutical industry

(3) China office of Fischer Chemicals AG (Switzerland)

Abatacept