Daclizumab

1. Product Name: Daclizumab 2. CAS No.: 152923-56-3 3. Specfication: Injection 4. Protein content: 10.0~15.0 mg/ml

5. Specification of Daclizumab

Items	Speicification	results
Protein content	10.0~15.0 mg/ml	12.6mg/ml
Bioactivity	80~125%	83%
Identification by SDS-PAGE	It should br idnetical to that of the refernce solution	complies
Purity by SDS-PAGE	The percentage of immunoglobulin light chain and heavy chain should be not less than 95%	99%
Purity by SEC-HPLC	≥97.0%	100.0%
Molecular weight	Heavy chain: 50.0~60.0 kDa Light chain: 22.0~28.0kDa	53.7kDa 25.8kDa
Isoecletric Point	Identical to taht of reference standard	complies
residue of exogenous	≤100pg/25mg protein	complies
Residue of CHO host cell protein	No more than 0.03% of total protein	0.00019%
bacterial endotoxins	<0.5EU/mg protein	<0.5 EU/mg preotein
Residue of rProtein A	Not more than 0.005% of toeal protein	complies
Peptide map	Identical to that of the reference standard	complies
Sequence of 15Amino Acids at N-terminal (Performed by contract laboratory )	DIQMTQSPSTLSASV	complies
PH	6.7~7.1	6.9
Osmolarity	260~300mOsmol/kg	289 mOsmol/kg
conclusion	The quality of this batch bulk product complies with Specification

6. Function.

It mainly to apply in prevention  AR (acute allograft rejection) after kiney transplantation.

Daclizumab is an immunosuppressive huamanized lg G1, monoclonal antibody produced by recombinant DNA technology  that binds specifically to the alpha sbuunit (p55 alpha, CD25, or TAAC Subunit) of the human high-affinity interleukin-2(IL-2), receptor that is wxpressed on the surface of activated lymphocytes.

7. About cooperation

As a high-tech content biological agents, sincerely we can delevop successful long-term cooperation for Daclizumab preparation. we can support each other

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Sinoway's Advantages:

(1) ISO 9001:2008 certificated company

(2) 26 years in pharmaceutical industry

(3) China office of Fischer Chemicals AG (Switzerland)

Daclizumab